Spina bifida is a defect resulting from failure of closure of the posterior neuropore, occurring anywhere along the spinal axis, but most commonly involving the lumbosacral region (63% of cases). Exposure of neural elements to amniotic fluid and meconium may lead to severe functional impairment.
Spina bifida is a defect resulting from failure of closure of the posterior neuropore, occurring anywhere along the spinal axis, but most commonly involving the lumbosacral region (63% of cases). Exposure of neural elements to amniotic fluid and meconium may lead to severe functional impairment.