Cytokines may signal cells close to the cell that released them, or they can travel great distances to relay their message. - Autocrine signaling: Cytokines can bind to receptors on the same cell that released it. - Paracrine signaling: Cytokines can bind to receptors on nearby cells. - Endocrine signaling: Cytokines can bind to receptors on cells located far away from the cell that released the cytokines. (Clevelandclinic)
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